HitPredict

Interactor 1: RAG1 (P15918)
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Interactor 2: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	26124138, 19118899
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1043 Hs			1 147
+	Hs
		551434 RAG1_HUMAN (1-1043): 0: 1703: 100.00		UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12
+	Hs
		849377 COP1_HUMAN (278-587): 9.57e-53: 200: 20.48		UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00
+	Hs
		919794 COP1_HUMAN (278-587): 9.57e-53: 200: 20.48		UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12
+	Hs
		895854 COP1_HUMAN (278-587): 9.57e-53: 200: 20.48		UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44
+	Hs
		1246146 COP1_HUMAN (278-587): 9.57e-53: 200: 20.48		UB2E2_HUMAN (4-146): 3.11e-74: 221: 62.94
+	Hs
		1285831 TRI43_HUMAN (279-594): 1.08e-47: 178: 14.59		UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84
+	Hs
		849399 TRI43_HUMAN (279-594): 1.08e-47: 178: 14.59		UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00
+	Hs
		851851 COP1_HUMAN (278-587): 9.57e-53: 200: 20.48		UB2E1_HUMAN (4-146): 3.94e-72: 216: 62.94
+	Hs
		919816 TRI43_HUMAN (279-594): 1.08e-47: 178: 14.59		UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12
+	Hs
		895870 TRI43_HUMAN (279-594): 1.08e-47: 178: 14.59		UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44
+	Hs
		849406 TRI11_HUMAN (278-618): 9.47e-40: 156: 18.21		UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00
+	Hs
		1163056 TRAF7_HUMAN (181-413): 9.52e-38: 153: 15.59		UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84
+	Hs
		919822 TRI11_HUMAN (278-618): 9.47e-40: 156: 18.21		UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12
+	Hs
		849344 TRAF7_HUMAN (181-413): 9.52e-38: 153: 15.59		UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00
+	Hs
		895876 TRI11_HUMAN (278-618): 9.47e-40: 156: 18.21		UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44
+	Hs
		849438 TRIM7_HUMAN (288-563): 3.13e-38: 152: 16.83		UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00
+	Hs
		919755 TRAF7_HUMAN (181-413): 9.52e-38: 153: 15.59		UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12
+	Hs
		851867 TRI11_HUMAN (278-618): 9.47e-40: 156: 18.21		UB2E1_HUMAN (4-146): 3.94e-72: 216: 62.94
+	Dm
		715103 Q9W3I9_DROME (285-462): 6.42e-40: 156: 17.78		UBE2N_DROME (4-147): 1.38e-72: 215: 47.92
+	Hs
		896517 TRI11_HUMAN (278-618): 9.47e-40: 156: 18.21		UBE2N_HUMAN (4-147): 1.92e-68: 205: 45.83