HitPredict

Interactor 1: ACHB2 (P12390)
Neuronal acetylcholine receptor subunit beta-2 (Neuronal acetylcholine receptor non-alpha-1 chain) (N-alpha 1)
Gene: Chrnb2

Interactor 2: ACHA7 (Q05941)
Neuronal acetylcholine receptor subunit alpha-7 (nAChR7) (Nicotinic acetylcholine receptor subunit alpha-7)
Gene: Chrna7

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19176801
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0001666 - response to hypoxia
GO:0005886 - plasma membrane
GO:0005892 - acetylcholine-gated channel complex
GO:0006816 - calcium ion transport
GO:0007165 - signal transduction
and 31 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 500
Rn

1 502
+ Hs
+ Gg
+ Gg
+ Rn
+ Rn
+ Gg
+ Hs
+ Gg
+ Gg
+ Hs
+ Hs
+ Hs
+ Gg
+ Rn
+ Mm
+ Hs
+ Gg

Service provided by Combinatics, Japan

Last updated: 11Aug2025