HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	28205554
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 156
+	Hs
		607909 FGFR4_HUMAN (13-802): 0: 750: 100.00		CDN2B_HUMAN (3-136): 4.71e-52: 163: 81.34
+	Hs
		608197 FGFR4_HUMAN (13-802): 0: 750: 100.00		ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59
+	Hs
		607910 FGFR4_HUMAN (13-802): 0: 750: 100.00		CDN2C_HUMAN (21-135): 1.37e-25: 97.4: 28.21
+	Hs
		507954 FGFR1_HUMAN (3-794): 0: 706: 54.76		ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37
+	Hs
		507971 FGFR1_HUMAN (3-794): 0: 706: 54.76		ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13
+	Hs
		507831 FGFR1_HUMAN (3-794): 0: 706: 54.76		ANK1_HUMAN (2-130): 2.4e-33: 125: 24.62
+	Hs
		508268 FGFR1_HUMAN (3-794): 0: 706: 54.76		ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59
+	Hs
		608115 FGFR4_HUMAN (13-802): 0: 750: 100.00		TANC1_HUMAN (56-154): 1.3e-14: 71.9: 21.00
+	Hs
		608184 FGFR4_HUMAN (13-802): 0: 750: 100.00		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		601612 FGFR2_HUMAN (4-797): 0: 737: 56.44		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		474791 FGFR3_HUMAN (5-799): 0: 712: 61.07		POTEI_HUMAN (49-152): 1.58e-18: 83.1: 13.89
+	Hs
		508185 FGFR1_HUMAN (3-794): 0: 706: 54.76		TANC1_HUMAN (56-154): 1.3e-14: 71.9: 21.00
+	Hs
		508236 FGFR1_HUMAN (3-794): 0: 706: 54.76		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21
+	Hs
		665376 EPHA3_HUMAN (4-778): 0: 595: 18.34		CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00
+	Hs
		665163 EPHA2_HUMAN (4-789): 0: 573: 19.58		CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00
+	Hs
		665164 EPHA2_HUMAN (4-789): 0: 573: 19.58		CDN2B_HUMAN (3-136): 4.71e-52: 163: 81.34
+	Hs
		665165 EPHA2_HUMAN (4-789): 0: 573: 19.58		CDN2C_HUMAN (21-135): 1.37e-25: 97.4: 28.21
+	Hs
		665439 EPHA3_HUMAN (4-778): 0: 595: 18.34		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		872504 EPHA5_HUMAN (4-771): 0: 580: 18.81		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		665360 EPHA2_HUMAN (4-789): 0: 573: 19.58		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48