HitPredict

Interactor 1: TCPA (P12612)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)
Gene: TCP1

Interactor 2: RPD3 (P32561)
Histone deacetylase RPD3 (EC 3.5.1.98) (Transcriptional regulatory protein RPD3)
Gene: RPD3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	23878396
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 559 Sc			1 433
+	Hs
		881911 TCPG_HUMAN (4-555): 0: 575: 29.53		HDAC1_HUMAN (15-428): 0: 598: 60.87
+	Hs
		610651 TCPA_HUMAN (9-556): 0: 569: 62.23		HDAC1_HUMAN (15-428): 0: 598: 60.87
+	Hs
		882071 TCPG_HUMAN (4-555): 0: 575: 29.53		HDAC2_HUMAN (18-432): 0: 583: 61.69
+	Hs
		1110033 TCPH_HUMAN (4-556): 0: 555: 31.78		HDAC1_HUMAN (15-428): 0: 598: 60.87
+	Hs
		610808 TCPA_HUMAN (9-556): 0: 569: 62.23		HDAC2_HUMAN (18-432): 0: 583: 61.69
+	Sc
		739868 TCPG_YEAST (7-552): 0: 537: 28.75		RPD3_YEAST (1-433): 0: 599: 100.00
+	Hs
		188212 TCPG_HUMAN (4-555): 0: 575: 29.53		HDAC3_HUMAN (19-433): 0: 534: 57.31
+	Hs
		188166 TCPA_HUMAN (9-556): 0: 569: 62.23		HDAC3_HUMAN (19-433): 0: 534: 57.31
+	Sp
		149155 TCPE_SCHPO (17-550): 0: 581: 30.48		PHD1_SCHPO (4-414): 3.58e-179: 508: 50.60
+	Hs
		188351 TCPH_HUMAN (4-556): 0: 555: 31.78		HDAC3_HUMAN (19-433): 0: 534: 57.31
+	Sp
		148986 TCPA_SCHPO (4-558): 0: 569: 76.40		PHD1_SCHPO (4-414): 3.58e-179: 508: 50.60
+	Sc
		554028 TCPA_YEAST (1-559): 0: 589: 100.00		HOS2_YEAST (3-430): 3.68e-168: 481: 45.04
+	Sp
		149068 TCPH_SCHPO (1-557): 0: 560: 33.16		PHD1_SCHPO (4-414): 3.58e-179: 508: 50.60
+	Sp
		148949 TCPG_SCHPO (7-550): 0: 553: 29.78		PHD1_SCHPO (4-414): 3.58e-179: 508: 50.60
+	Mm
		1009970 TCPE_MOUSE (17-551): 0: 605: 29.55		HDAC4_MOUSE (1-418): 7e-134: 412: 22.77
+	Mm
		550725 TCPA_MOUSE (9-556): 0: 560: 60.95		HDAC4_MOUSE (1-418): 7e-134: 412: 22.77
+	Mm
		1009921 TCPH_MOUSE (4-558): 0: 559: 31.79		HDAC4_MOUSE (1-418): 7e-134: 412: 22.77
+	Hs
		882203 TCPG_HUMAN (4-555): 0: 575: 29.53		HDAC6_HUMAN (21-331): 1.59e-90: 299: 23.84
+	Hs
		610927 TCPA_HUMAN (9-556): 0: 569: 62.23		HDAC6_HUMAN (21-331): 1.59e-90: 299: 23.84
+	Hs
		1407610 TCPH_HUMAN (4-556): 0: 555: 31.78		HDAC6_HUMAN (21-331): 1.59e-90: 299: 23.84