HitPredict

Interactor 1: TCPA (P11983)
T-complex protein 1 subunit alpha (TCP-1-alpha) (EC 3.6.1.-) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A) (Tailless complex polypeptide 1B) (TCP-1-B)
Gene: Tcp1

Interactor 2: HDAC4 (Q6NZM9)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	31040226
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Mm			1 1076
+	Mm
		1009970 TCPE_MOUSE (4-532): 0: 609: 31.84		HDAC4_MOUSE (1-1065): 0: 841: 100.00
+	Mm
		1009921 TCPH_MOUSE (1-551): 0: 572: 34.64		HDAC4_MOUSE (1-1065): 0: 841: 100.00
+	Hs
		610944 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC5_HUMAN (1-1076): 0: 662: 54.58
+	Hs
		882219 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC5_HUMAN (1-1076): 0: 662: 54.58
+	Hs
		1407631 TCPH_HUMAN (1-543): 0: 559: 34.06		HDAC5_HUMAN (1-1076): 0: 662: 54.58
+	Hs
		610651 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC1_HUMAN (643-1040): 1.08e-162: 491: 24.03
+	Hs
		610808 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC2_HUMAN (664-1074): 7.02e-161: 486: 22.84
+	Hs
		188166 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC3_HUMAN (647-1073): 2.26e-153: 464: 20.77
+	Hs
		881911 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC1_HUMAN (643-1040): 1.08e-162: 491: 24.03
+	Hs
		882071 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC2_HUMAN (664-1074): 7.02e-161: 486: 22.84
+	Hs
		188212 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC3_HUMAN (647-1073): 2.26e-153: 464: 20.77
+	Hs
		1110033 TCPH_HUMAN (1-543): 0: 559: 34.06		HDAC1_HUMAN (643-1040): 1.08e-162: 491: 24.03
+	Hs
		188351 TCPH_HUMAN (1-543): 0: 559: 34.06		HDAC3_HUMAN (647-1073): 2.26e-153: 464: 20.77
+	Sc
		553963 TCPA_YEAST (4-543): 0: 556: 61.17		RPD3_YEAST (634-1067): 3.89e-154: 466: 21.98
+	Hs
		610927 TCPA_HUMAN (1-556): 0: 628: 96.40		HDAC6_HUMAN (644-1033): 2.59e-111: 376: 36.74
+	Hs
		882203 TCPG_HUMAN (5-555): 0: 588: 32.49		HDAC6_HUMAN (644-1033): 2.59e-111: 376: 36.74
+	Hs
		1407610 TCPH_HUMAN (1-543): 0: 559: 34.06		HDAC6_HUMAN (644-1033): 2.59e-111: 376: 36.74
+	Sp
		148949 TCPG_SCHPO (1-539): 0: 568: 29.89		PHD1_SCHPO (670-1000): 1.12e-23: 107: 29.11
+	Sp
		148986 TCPA_SCHPO (2-545): 0: 561: 64.42		PHD1_SCHPO (670-1000): 1.12e-23: 107: 29.11
+	Sc
		554028 TCPA_YEAST (4-543): 0: 556: 61.17		HOS2_YEAST (633-950): 4.71e-24: 108: 28.09