Interactor 1: ITB4 (P16144)
Integrin beta-4 (GP150) (CD antigen CD104)
Gene: ITGB4

Interactor 2: ITA3 (P26006)
Integrin alpha-3 (CD49 antigen-like family member C) (FRP-2) (Galactoprotein B3) (GAPB3) (VLA-3 subunit alpha) (CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain]
Gene: ITGA3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16878156
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_2~Integrin_alpha2, I-EGF_1~Integrin_alpha2, Integrin_B_tail~Integrin_alpha2, FG-GAP~Integrin_beta, Integrin_alpha2~Integrin_beta, Integrin_alpha2~PSI_integrin
Common GO terms GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007160 - cell-matrix adhesion
GO:0007229 - integrin-mediated signaling pathway
and 8 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1822
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024