HitPredict

Interactor 1: PSA1 (P12881)
Proteasome subunit alpha type-1 (PROS-Dm35) (Proteasome 35 kDa subunit)
Gene: Prosalpha6

Interactor 2: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome, AAA~Proteasome_A_N, AAA_lid_3~Proteasome_A_N
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 279 Dm			1 433
+	Dm
		652748 PSA71_DROME (4-236): 4.11e-102: 299: 30.93		Q7KMQ0_DROME (1-433): 3.94e-145: 422: 100.00
+	Hs
		680794 PSA1_HUMAN (1-269): 1.17e-102: 301: 52.42		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Hs
		700565 PSA5_HUMAN (1-239): 6.43e-95: 281: 30.08		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Dm
		198018 PSA1_DROME (1-279): 8.23e-111: 322: 100.00		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Dm
		556726 PSA1_DROME (1-279): 8.23e-111: 322: 100.00		Q9V405_DROME (1-425): 2.69e-118: 352: 35.29
+	Dm
		556649 PSA1_DROME (1-279): 8.23e-111: 322: 100.00		PRS4_DROME (1-430): 3.95e-117: 351: 38.89
+	Dm
		556822 PSA1_DROME (1-279): 8.23e-111: 322: 100.00		Q9W414_DROME (33-429): 1.46e-116: 347: 42.75
+	Dm
		198021 PSA71_DROME (4-236): 4.11e-102: 299: 30.93		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Hs
		680834 PSA1_HUMAN (1-269): 1.17e-102: 301: 52.42		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		680835 PSA1_HUMAN (1-269): 1.17e-102: 301: 52.42		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Dm
		652769 PSA71_DROME (4-236): 4.11e-102: 299: 30.93		Q9V405_DROME (1-425): 2.69e-118: 352: 35.29
+	Hs
		680837 PSA1_HUMAN (1-269): 1.17e-102: 301: 52.42		PRS10_HUMAN (34-429): 9.58e-118: 350: 41.60
+	Dm
		652730 PSA71_DROME (4-236): 4.11e-102: 299: 30.93		PRS4_DROME (1-430): 3.95e-117: 351: 38.89
+	Hs
		680808 PSA1_HUMAN (1-269): 1.17e-102: 301: 52.42		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84
+	Dm
		652818 PSA71_DROME (4-236): 4.11e-102: 299: 30.93		Q9W414_DROME (33-429): 1.46e-116: 347: 42.75
+	Dm
		875021 Q9VK14_DROME (1-268): 1.51e-99: 294: 58.48		PRS4_DROME (1-430): 3.95e-117: 351: 38.89
+	Hs
		700600 PSA5_HUMAN (1-239): 6.43e-95: 281: 30.08		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		700601 PSA5_HUMAN (1-239): 6.43e-95: 281: 30.08		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Hs
		700574 PSA5_HUMAN (1-239): 6.43e-95: 281: 30.08		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84
+	Dm
		1478932 Q9VK14_DROME (1-268): 1.51e-99: 294: 58.48		Q9VTQ9_DROME (111-416): 1.43e-102: 312: 48.37