HitPredict

Interactor 1: MYH1 (P12882)
Myosin-1 (Myosin heavy chain 1) (Myosin heavy chain 2x) (MyHC-2x) (Myosin heavy chain IIx/d) (MyHC-IIx/d) (Myosin heavy chain, skeletal muscle, adult 1)
Gene: MYH1

Interactor 2: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38334954
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1939 Hs			1 1101
+	Hs
		1313578 MYH4_HUMAN (1-1939): 0: 1143: 94.07		SMC5_HUMAN (1-1101): 2.63e-125: 412: 100.00
+	Hs
		563081 MYH4_HUMAN (1-1939): 0: 1143: 94.07		MYH8_HUMAN (523-990): 3.38e-17: 89.7: 9.40
+	Hs
		556973 MYH4_HUMAN (1-1939): 0: 1143: 94.07		MYH7_HUMAN (448-973): 1.5e-14: 80.9: 10.44
+	Mm
		1037835 MYH1_MOUSE (1-1939): 0: 1134: 96.19		MYH6_MOUSE (498-968): 1.5e-13: 77.8: 11.58
+	Rn
		386940 MYH6_RAT (3-1939): 0: 1122: 80.51		MYH6_RAT (498-951): 1.16e-13: 78.2: 12.01
+	Hs
		562992 MYH6_HUMAN (3-1939): 0: 1120: 80.40		MYH6_HUMAN (498-968): 1.06e-13: 78.2: 11.58
+	Mm
		1037830 MYH6_MOUSE (3-1934): 0: 1113: 80.69		MYH6_MOUSE (498-968): 1.5e-13: 77.8: 11.58
+	Mm
		563088 MYH6_MOUSE (3-1934): 0: 1113: 80.69		MYH8_MOUSE (557-938): 3.74e-13: 76.7: 12.57
+	Hs
		772896 MYH9_HUMAN (1407-1939): 4.51e-32: 139: 14.98		SMC5_HUMAN (1-1101): 2.63e-125: 412: 100.00
+	Hs
		776872 MYH11_HUMAN (940-1939): 1.26e-63: 243: 18.65		SMC3_HUMAN (51-1090): 1.06e-48: 191: 11.52
+	Hs
		563078 MYH13_HUMAN (1069-1939): 8.11e-50: 197: 14.93		MYH8_HUMAN (523-990): 3.38e-17: 89.7: 9.40
+	Hs
		556892 MYH7_HUMAN (1266-1938): 1.92e-42: 173: 14.41		MYH7_HUMAN (448-973): 1.5e-14: 80.9: 10.44
+	Mm
		59762 MYH7B_MOUSE (1266-1938): 1.08e-34: 148: 14.06		MYH6_MOUSE (498-968): 1.5e-13: 77.8: 11.58
+	Hs
		556902 MYH9_HUMAN (1407-1939): 4.51e-32: 139: 14.98		MYH7_HUMAN (448-973): 1.5e-14: 80.9: 10.44
+	Hs
		535921 MYH3_HUMAN (711-1380): 6.06e-27: 122: 14.99		MYH6_HUMAN (498-968): 1.06e-13: 78.2: 11.58