HitPredict

Interactor 1: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Interactor 2: IL3RA (P26951)
Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (CD antigen CD123)
Gene: IL3RA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 378
+	Hs
		500941 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		GHR_HUMAN (89-347): 8.09e-42: 156: 14.78
+	Hs
		557612 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		CNTFR_HUMAN (41-303): 1.14e-40: 149: 14.49
+	Hs
		557644 NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00		EPHB1_HUMAN (42-327): 2.1e-38: 148: 13.10
+	Hs
		208997 NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24		EPHA8_HUMAN (67-330): 2.75e-37: 145: 12.46
+	Hs
		560468 TEC_HUMAN (27-377): 4.7e-38: 146: 17.63		PRLR_HUMAN (101-353): 2.02e-58: 201: 16.79
+	Hs
		548790 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		CSF2R_HUMAN (3-372): 3.94e-72: 232: 29.29
+	Hs
		789068 ABL2_HUMAN (83-375): 1.75e-33: 134: 23.05		EPHA7_HUMAN (66-284): 7.33e-40: 152: 13.50
+	Hs
		500948 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		GHR_HUMAN (89-347): 8.09e-42: 156: 14.78
+	Mm
		643058 P85A_MOUSE (241-376): 1.59e-22: 101: 19.57		IL2RG_MOUSE (93-368): 1.93e-43: 156: 17.93
+	Hs
		129180 P85B_HUMAN (100-376): 1.85e-21: 98.3: 16.61		GHR_HUMAN (89-347): 8.09e-42: 156: 14.78
+	Hs
		581163 GRAP_HUMAN (5-251): 9.35e-27: 107: 20.00		EPOR_HUMAN (102-363): 4.2e-39: 147: 18.21
+	Hs
		655380 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		EPHA7_HUMAN (66-284): 7.33e-40: 152: 13.50
+	Mm
		540266 P85A_MOUSE (241-376): 1.59e-22: 101: 19.57		EPOR_MOUSE (102-363): 4.92e-39: 147: 18.35
+	Hs
		581150 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		EPOR_HUMAN (102-363): 4.2e-39: 147: 18.21
+	Hs
		655221 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		EPHA8_HUMAN (67-330): 2.75e-37: 145: 12.46
+	Hs
		655220 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		EPHA3_HUMAN (60-329): 8.89e-36: 140: 11.00
+	Hs
		129209 P85B_HUMAN (100-376): 1.85e-21: 98.3: 16.61		EPHA3_HUMAN (60-329): 8.89e-36: 140: 11.00
+	Hs
		562513 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		IL7RA_HUMAN (181-348): 2.43e-28: 117: 15.26
+	Hs
		655246 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		IL6RB_HUMAN (35-344): 3.57e-12: 69.8: 12.81
+	Hs
		655234 P85A_HUMAN (241-376): 1.37e-22: 101: 19.57		IL3RB_HUMAN (108-295): 4.67e-12: 69.5: 12.39