HitPredict

Interactor 1: H13 (P16402)
Histone H1.3 (Histone H1c) (Histone H1s-2)
Gene: H1-3

Interactor 2: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36042349
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 221 Hs			1 346
+	Rn
		413197 H1T_RAT (1-219): 3.85e-36: 127: 49.32		Q6P751_RAT (9-307): 5.12e-150: 425: 43.52
+	Hs
		559328 H13_HUMAN (1-182): 1.29e-30: 114: 100.00		CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85
+	Hs
		559612 H12_HUMAN (30-174): 6.93e-24: 96.3: 88.28		CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00
+	Rn
		88903 H11_RAT (1-121): 6.42e-22: 91.3: 68.85		Q6P751_RAT (9-307): 5.12e-150: 425: 43.52
+	Hs
		558990 H15_HUMAN (1-116): 3.39e-20: 87.1: 82.20		CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85
+	Hs
		488949 H14_HUMAN (1-116): 3.93e-21: 89.4: 93.10		CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00
+	Hs
		625377 H11_HUMAN (39-182): 9.17e-18: 80.1: 61.81		CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85
+	Hs
		414717 H13_HUMAN (1-182): 1.29e-30: 114: 100.00		CDK1_HUMAN (9-298): 6.62e-135: 387: 43.00
+	Hs
		841171 H11_HUMAN (39-182): 9.17e-18: 80.1: 61.81		CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00
+	Mm
		794656 H15_MOUSE (1-204): 3.87e-22: 92.1: 70.59		CDK2_MOUSE (9-307): 1.16e-141: 406: 37.54
+	Mm
		550489 H12_MOUSE (33-116): 1.07e-16: 77.4: 97.62		CDK2_MOUSE (9-307): 1.16e-141: 406: 37.54
+	Hs
		559654 H12_HUMAN (30-174): 6.93e-24: 96.3: 88.28		CDK5_HUMAN (9-301): 1.39e-134: 386: 45.09
+	Rn
		88899 H11_RAT (1-121): 6.42e-22: 91.3: 68.85		CDK1_RAT (9-298): 2.99e-134: 385: 43.35
+	Hs
		489003 H14_HUMAN (1-116): 3.93e-21: 89.4: 93.10		CDK5_HUMAN (9-301): 1.39e-134: 386: 45.09
+	Hs
		414716 H15_HUMAN (1-116): 3.39e-20: 87.1: 82.20		CDK1_HUMAN (9-298): 6.62e-135: 387: 43.00
+	Hs
		559065 H15_HUMAN (1-116): 3.39e-20: 87.1: 82.20		CDK5_HUMAN (9-301): 1.39e-134: 386: 45.09
+	Hs
		414874 H11_HUMAN (39-182): 9.17e-18: 80.1: 61.81		CDK1_HUMAN (9-298): 6.62e-135: 387: 43.00
+	Hs
		960270 H11_HUMAN (39-182): 9.17e-18: 80.1: 61.81		CDK5_HUMAN (9-301): 1.39e-134: 386: 45.09
+	Mm
		509461 H12_MOUSE (33-116): 1.07e-16: 77.4: 97.62		CDK1_MOUSE (9-298): 3.17e-133: 383: 43.35
+	Mm
		509472 H11_MOUSE (1-122): 1.46e-16: 77: 69.11		CDK1_MOUSE (9-298): 3.17e-133: 383: 43.35