HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25963833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016887 - ATP hydrolysis activity GO:0019899 - enzyme binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 643 Hs			1 904
+	Hs
		713924 HS71L_HUMAN (1-643): 0: 960: 79.32		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		503683 HSP7C_HUMAN (4-615): 0: 940: 79.25		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		832264 HSP72_HUMAN (3-643): 0: 925: 77.45		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		503540 HSP7C_HUMAN (4-615): 0: 940: 79.25		MCM4_HUMAN (2-885): 0: 847: 28.42
+	Hs
		564019 HSP76_HUMAN (1-643): 0: 970: 100.00		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		708559 HS71L_HUMAN (1-643): 0: 960: 79.32		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		503541 HSP7C_HUMAN (4-615): 0: 940: 79.25		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		708586 HSP72_HUMAN (3-643): 0: 925: 77.45		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		708939 Q53FC7_HUMAN (1-643): 0: 965: 99.22		MCM7_HUMAN (188-886): 0: 707: 27.35
+	Hs
		503542 HSP7C_HUMAN (4-615): 0: 940: 79.25		MCM7_HUMAN (188-886): 0: 707: 27.35