HitPredict

Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	33961781, 35271311, 32707033, 23455922
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019904 - protein domain specific binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 249
+	Hs
		610790 KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		310497 KAPCA_HUMAN (1-351): 9.98e-166: 467: 100.00		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310510 KAPCB_HUMAN (1-351): 7.27e-164: 463: 92.88		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310509 KAPCG_HUMAN (1-351): 2.31e-162: 459: 82.91		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12