Protein: KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

Gene: KAP1, Prkar1b
Organism: Mus musculus
Interactions: 86
UniProt ID: P12849

Gene Ontology (top 5):
GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005737 - cytoplasm
GO:0005771 - multivesicular body
GO:0005886 - plasma membrane
GO:0005952 - cAMP-dependent protein kinase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

312815

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

15

High-throughput

0.691

High

556496

TNIK
Traf2 and NCK-interacting protein kinase

1

4

High-throughput

0.691

High

266753

LNX1
E3 ubiquitin-protein ligase LNX

1

5

High-throughput

0.618

High

548931

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

3

High-throughput

0.618

High

556474

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

18

High-throughput

0.618

High

556483

ZO1
Tight junction protein 1

1

1

High-throughput

0.618

High

556492

KPCG
Protein kinase C gamma type

1

11

High-throughput

0.618

High

556494

KPCB
Protein kinase C beta type

1

11

High-throughput

0.618

High

556523

LNX2
Ligand of Numb protein X 2

1

5

High-throughput

0.618

High

556537

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]

1

19

High-throughput

0.618

High

556546

KCNQ2
Potassium voltage-gated channel subfamily KQT member 2

1

9

High-throughput

0.618

High

556511

LRRC7
Leucine-rich repeat-containing protein 7

1

0

High-throughput

0.586

High

237008

CAC1B
Voltage-dependent N-type calcium channel subunit alpha-1B

1

2

High-throughput

0.553

High

556525

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

3

High-throughput

0.553

High

551371

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.479

High

556475

NCAM1
Neural cell adhesion molecule 1

1

2

High-throughput

0.479

High

556476

GRIA2
Glutamate receptor 2

1

3

High-throughput

0.479

High

556478

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

556481

GPM6A
Neuronal membrane glycoprotein M6-a

1

1

High-throughput

0.479

High

556488

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

556489

RL18A
Large ribosomal subunit protein eL20

1

1

High-throughput

0.479

High

556490

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.479

High

556493

TBA4A
Tubulin alpha-4A chain

1

2

High-throughput

0.479

High

556495

SPRL1
SPARC-like protein 1

1

2

High-throughput

0.479

High

556497

CXAR
Coxsackievirus and adenovirus receptor homolog

1

2

High-throughput

0.479

High

556502

NACA
Nascent polypeptide-associated complex subunit alpha

1

2

High-throughput

0.479

High

556505

KINH
Kinesin-1 heavy chain

1

3

High-throughput

0.479

High

556506

SYN2
Synapsin-2

1

1

High-throughput

0.479

High

556510

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.479

High

556516

PYGB
Glycogen phosphorylase, brain form

1

1

High-throughput

0.479

High

556518

DP13A
DCC-interacting protein 13-alpha

1

1

High-throughput

0.479

High

556519

MARE2
Microtubule-associated protein RP/EB family member 2

1

3

High-throughput

0.479

High

556542

PLEC
Plectin

1

1

High-throughput

0.479

High

556543

KAD1
Adenylate kinase isoenzyme 1

1

1

High-throughput

0.479

High

556545

VAPA
Vesicle-associated membrane protein-associated protein A

1

6

High-throughput

0.479

High

73159

DLGP4
Disks large-associated protein 4

1

0

High-throughput

0.458

High

204266

PHB2
Prohibitin-2

1

0

High-throughput

0.458

High

237135

SNG1
Synaptogyrin-1

1

0

High-throughput

0.458

High

556479

MRP
MARCKS-related protein

1

0

High-throughput

0.458

High

556485

MOT1
Monocarboxylate transporter 1

1

0

High-throughput

0.458

High

556486

PDCD5
Programmed cell death protein 5

1

0

High-throughput

0.458

High

556487

SNP25
Synaptosomal-associated protein 25

1

0

High-throughput

0.458

High

556491

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

556499

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

0

High-throughput

0.458

High

556503

GSLG1
Golgi apparatus protein 1

1

0

High-throughput

0.458

High

556504

ELAV4
ELAV-like protein 4

1

0

High-throughput

0.458

High

556513

NRCAM
Neuronal cell adhesion molecule

1

0

High-throughput

0.458

High

556517

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

0

High-throughput

0.458

High

556524

BASP1
Brain acid soluble protein 1

1

0

High-throughput

0.458

High

556527

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

0

High-throughput

0.458

High

556532

VATG1
V-type proton ATPase subunit G 1

1

0

High-throughput

0.458

High

556535

SPP
Signal peptide peptidase

1

0

High-throughput

0.458

High

556540

MESD
LRP chaperone MESD

1

0

High-throughput

0.458

High

379593

IGHM
Immunoglobulin heavy constant mu [Cleaved into: Mu' chain

1

2

High-throughput

0.457

High

480957

NUCL
Nucleolin

1

3

High-throughput

0.437

High

553482

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

1

High-throughput

0.437

High

556498

TBB5
Tubulin beta-5 chain

1

3

High-throughput

0.437

High

556500

DJC11
DnaJ homolog subfamily C member 11

1

1

High-throughput

0.437

High

556508

SPKAP
A-kinase anchor protein SPHKAP

1

10

High-throughput

0.437

High

556512

FACD2
Fanconi anemia group D2 protein homolog

1

2

High-throughput

0.437

High

556521

Q8R5C0
Metaxin

1

1

High-throughput

0.437

High

556522

SFXN3
Sideroflexin-3

1

1

High-throughput

0.437

High

556526

SFXN5
Sideroflexin-5

1

1

High-throughput

0.437

High

556530

RRBP1
Ribosome-binding protein 1

1

1

High-throughput

0.437

High

556531

Q9CQB4
Cytochrome b-c1 complex subunit 7

1

1

High-throughput

0.437

High

556539

AP3S1
AP-3 complex subunit sigma-1

1

2

High-throughput

0.437

High

556515

ING4
Inhibitor of growth protein 4

1

1

High-throughput

0.417

High

485913

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.249

Low

556477

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

0

High-throughput

0.249

Low

556480

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.249

Low

556482

NCPR
NADPH--cytochrome P450 reductase

1

0

High-throughput

0.249

Low

556484

FKBP2
Peptidyl-prolyl cis-trans isomerase FKBP2

1

0

High-throughput

0.249

Low

556501

PSB6
Proteasome subunit beta type-6

1

0

High-throughput

0.249

Low

556507

HELZ
Probable helicase with zinc finger domain

1

0

High-throughput

0.249

Low

556509

MLEC
Malectin

1

0

High-throughput

0.249

Low

556514

Q8BIX2
GCN1 activator of EIF2AK4

1

0

High-throughput

0.249

Low

556520

K0513
Uncharacterized protein KIAA0513

1

0

High-throughput

0.249

Low

556528

DHRS1
Dehydrogenase/reductase SDR family member 1

1

0

High-throughput

0.249

Low

556529

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.249

Low

556533

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.249

Low

556536

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

High-throughput

0.249

Low

556538

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.249

Low

556541

XPO2
Exportin-2

1

0

High-throughput

0.249

Low

556544

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.249

Low

556534

SCOT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025