HitPredict

Interactor 1: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005925 - focal adhesion
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1338 Hs			1 999
+	Hs
		729392 VGFR3_HUMAN (21-1330): 0: 755: 37.92		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		729325 VGFR3_HUMAN (21-1330): 0: 755: 37.92		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320822 VGFR3_HUMAN (21-1330): 0: 755: 37.92		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		609631 FGFR3_HUMAN (1-353): 3.63e-53: 203: 11.78		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		452500 PGFRB_HUMAN (25-560): 1.37e-48: 191: 20.73		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		508291 FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		320811 FGFR3_HUMAN (1-353): 3.63e-53: 203: 11.78		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		609191 FGFR3_HUMAN (1-353): 3.63e-53: 203: 11.78		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		608207 FGFR4_HUMAN (41-238): 1.53e-27: 122: 11.85		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		738300 FLT3_HUMAN (14-570): 5.07e-23: 108: 13.57		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		320803 FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		503438 FGFR3_HUMAN (1-353): 3.63e-53: 203: 11.78		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		507880 FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		507924 FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		507836 FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70