HitPredict

Interactor 1: A1Z7C4 (A1Z7C4)
LDL receptor protein 1, isoform G
Gene: LRP1

Interactor 2: LAMC1 (P15215)
Laminin subunit gamma-1 (Laminin B2 chain)
Gene: LanB2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.659

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Laminin_EGF~Ldl_recept_b
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 4730 Dm			1 1639
+	Dm
		52869 A1Z7C4_DROME (1-4730): 0: 3173: 100.00		LAMB1_DROME (16-1578): 4.86e-170: 562: 21.43
+	Dm
		52875 A1Z7C4_DROME (1-4730): 0: 3173: 100.00		LAMA_DROME (907-1156): 2.36e-10: 68: 14.58
+	Dm
		451718 NOTCH_DROME (2516-2831): 9.38e-10: 68: 11.28		LAMC1_DROME (1-1639): 0: 1042: 100.00
+	Hs
		535812 NID1_HUMAN (2590-2831): 9.43e-09: 64.5: 15.73		LAMC1_HUMAN (54-1627): 0: 879: 39.52
+	Mm
		384329 NID1_MOUSE (3463-3750): 5.34e-09: 65.3: 12.33		LAMC1_MOUSE (52-1627): 0: 866: 39.28
+	Dm
		53928 NDG_DROME (3365-3600): 8.85e-09: 64.5: 15.45		LAMB1_DROME (16-1578): 4.86e-170: 562: 21.43
+	Hs
		857370 NOTC1_HUMAN (2520-2867): 6.13e-10: 68.4: 11.11		NOTC1_HUMAN (541-1156): 1.75e-52: 206: 12.81
+	Hs
		572704 NID1_HUMAN (2590-2831): 9.43e-09: 64.5: 15.73		LAMC3_HUMAN (760-1637): 9.52e-49: 193: 16.00
+	Dm
		451712 NOTCH_DROME (2516-2831): 9.38e-10: 68: 11.28		NOTCH_DROME (759-1129): 2.17e-30: 133: 14.32
+	Dm
		451968 Q9W4Y4_DROME (60-183): 3.48e-09: 65.9: 37.10		NOTCH_DROME (759-1129): 2.17e-30: 133: 14.32
+	Dm
		53927 NDG_DROME (3365-3600): 8.85e-09: 64.5: 15.45		NOTCH_DROME (759-1129): 2.17e-30: 133: 14.32
+	Hs
		857423 NOTC1_HUMAN (2520-2867): 6.13e-10: 68.4: 11.11		NOTC2_HUMAN (266-617): 1.76e-19: 98: 13.28
+	Hs
		857591 NOTC1_HUMAN (2520-2867): 6.13e-10: 68.4: 11.11		NOTC3_HUMAN (271-592): 2.79e-18: 94.2: 14.62
+	Hs
		1060935 LRP1_HUMAN (95-338): 9.5e-10: 68: 11.34		NOTC3_HUMAN (271-592): 2.79e-18: 94.2: 14.62
+	Dm
		451745 NOTCH_DROME (2516-2831): 9.38e-10: 68: 11.28		LAMA_DROME (907-1156): 2.36e-10: 68: 14.58
+	Dm
		53931 NDG_DROME (3365-3600): 8.85e-09: 64.5: 15.45		LAMA_DROME (907-1156): 2.36e-10: 68: 14.58
+	Mm
		522313 NID1_MOUSE (3463-3750): 5.34e-09: 65.3: 12.33		PGBM_MOUSE (405-650): 8.54e-09: 63: 18.07