HitPredict

Interactor 1: LIN12 (P14585)
Protein lin-12 (Abnormal cell lineage protein 12) (Notch-like protein lin-12) [Cleaved into: lin-12/Notch intracellular domain]
Gene: lin-12

Interactor 2: SEL10 (Q93794)
F-box/WD repeat-containing protein sel-10 (Egg laying defective protein 41) (Suppressor/enhancer of lin-12 protein 10)
Gene: sel-10

Species: Caenorhabditis elegans

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 9389650, 10615043, 14704431
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~F-box-like
Common GO terms GO:0040028 - regulation of vulval development
GO:0045746 - negative regulation of Notch signaling pathway
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1429
Ce

1 587
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Last updated: 11Aug2025