HitPredict

Interactor 1: A4 (P14599)
Amyloid-beta-like protein
Gene: Appl

Interactor 2: Q9VX41 (Q9VX41)
LD29081p (X11L, isoform A)
Gene: X11L

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.80	0.776

Property	Details
Experiments	15976083, 12068070, 11912189
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	APP_amyloid~PID
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 887 Dm			1 1167
+	Dm
		572861 A4_DROME (1-887): 0: 1330: 100.00		Q9GQQ6_DROME (14-1167): 0: 1730: 99.57
+	Hs
		421954 A4_HUMAN (387-631): 2.77e-90: 304: 28.74		APBA1_HUMAN (746-1167): 3.34e-131: 423: 57.74
+	Mm
		551418 A4_MOUSE (387-631): 7.68e-92: 309: 29.13		APBA2_MOUSE (684-1167): 1.67e-122: 396: 50.80
+	Hs
		355058 A4_HUMAN (387-631): 2.77e-90: 304: 28.74		APBA3_HUMAN (745-1167): 8.62e-125: 397: 48.23
+	Hs
		422974 A4_HUMAN (387-631): 2.77e-90: 304: 28.74		APBA2_HUMAN (752-1167): 2.21e-121: 394: 57.24
+	Hs
		355076 APLP2_HUMAN (23-199): 8.62e-80: 275: 36.52		APBA3_HUMAN (745-1167): 8.62e-125: 397: 48.23
+	Hs
		1055349 APLP2_HUMAN (23-199): 8.62e-80: 275: 36.52		APBA2_HUMAN (752-1167): 2.21e-121: 394: 57.24
+	Mm
		551439 A4_MOUSE (387-631): 7.68e-92: 309: 29.13		DLG4_MOUSE (1067-1147): 3.57e-16: 85.7: 20.46
+	Hs
		421902 A4_HUMAN (387-631): 2.77e-90: 304: 28.74		DLG4_HUMAN (1067-1147): 3.66e-16: 85.7: 20.46