HitPredict

Interactor 1: KPYM (P14618)
Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) (p58)
Gene: PKM

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	31391242, 37554583
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 531 Hs			1 548
+	Hs
		572982 KPYM_HUMAN (1-531): 0: 801: 100.00		RO52_HUMAN (12-440): 1.48e-79: 259: 15.51
+	Hs
		573197 KPYM_HUMAN (1-531): 0: 801: 100.00		TRI63_HUMAN (8-326): 1.5e-79: 255: 61.88
+	Hs
		573088 KPYM_HUMAN (1-531): 0: 801: 100.00		TIF1B_HUMAN (18-534): 5.4e-67: 234: 15.37
+	Hs
		573176 KPYM_HUMAN (1-531): 0: 801: 100.00		TRI58_HUMAN (14-438): 2.72e-68: 230: 12.27
+	Hs
		573236 KPYM_HUMAN (1-531): 0: 801: 100.00		TRI31_HUMAN (12-426): 2.13e-68: 228: 17.35
+	Hs
		573283 KPYM_HUMAN (1-531): 0: 801: 100.00		TRI33_HUMAN (25-520): 3.13e-63: 226: 12.23
+	Hs
		720898 KPYR_HUMAN (6-530): 0: 744: 71.62		TRI33_HUMAN (25-520): 3.13e-63: 226: 12.23
+	Hs
		573143 KPYM_HUMAN (1-531): 0: 801: 100.00		TRI67_HUMAN (122-326): 8.36e-14: 76.3: 24.39