HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: LST8 (Q9BVC4)
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)
Gene: MLST8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 556 Hs			1 326
+	Hs
		826860 TCPG_HUMAN (5-550): 0: 593: 33.03		LST8_HUMAN (1-326): 1.45e-95: 287: 100.00
+	Hs
		573201 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57
+	Hs
		826601 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57
+	Hs
		573371 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1A_HUMAN (122-325): 1.44e-56: 190: 20.10
+	Hs
		573384 TCPA_HUMAN (1-556): 0: 630: 100.00		POC1B_HUMAN (119-325): 4.27e-53: 182: 18.36
+	Hs
		903467 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR5_HUMAN (79-326): 3.77e-74: 233: 20.57
+	Hs
		826772 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1A_HUMAN (122-325): 1.44e-56: 190: 20.10
+	Hs
		826784 TCPG_HUMAN (5-550): 0: 593: 33.03		POC1B_HUMAN (119-325): 4.27e-53: 182: 18.36
+	Hs
		1240450 TCPH_HUMAN (1-545): 0: 566: 34.84		POC1A_HUMAN (122-325): 1.44e-56: 190: 20.10
+	Hs
		196954 TCPA_HUMAN (1-556): 0: 630: 100.00		PRP4_HUMAN (157-324): 2.36e-27: 113: 18.75
+	Hs
		573346 TCPA_HUMAN (1-556): 0: 630: 100.00		WDR5B_HUMAN (200-322): 9.78e-28: 112: 26.83
+	Hs
		573412 TCPA_HUMAN (1-556): 0: 630: 100.00		SNR40_HUMAN (199-318): 3.98e-24: 102: 20.00
+	At
		660212 TCPA_ARATH (7-541): 0: 579: 66.17		LST81_ARATH (99-322): 1.96e-40: 145: 12.45
+	Hs
		196973 TCPG_HUMAN (5-550): 0: 593: 33.03		PRP4_HUMAN (157-324): 2.36e-27: 113: 18.75
+	Hs
		826748 TCPG_HUMAN (5-550): 0: 593: 33.03		WDR5B_HUMAN (200-322): 9.78e-28: 112: 26.83
+	Hs
		573456 TCPA_HUMAN (1-556): 0: 630: 100.00		KTNB1_HUMAN (14-199): 7.11e-09: 58.9: 22.46
+	At
		97123 TCPA_ARATH (7-541): 0: 579: 66.17		F4J7K1_ARATH (93-322): 2.55e-26: 105: 13.75
+	Hs
		197078 TCPH_HUMAN (1-545): 0: 566: 34.84		PRP4_HUMAN (157-324): 2.36e-27: 113: 18.75
+	Hs
		1202777 TCPH_HUMAN (1-545): 0: 566: 34.84		WDR5B_HUMAN (200-322): 9.78e-28: 112: 26.83
+	Hs
		792942 TCPG_HUMAN (5-550): 0: 593: 33.03		LIS1_HUMAN (259-324): 8.45e-12: 67.3: 24.24