Interactor 1: PTC (P18502)
Protein patched (Hedgehog receptor)
Gene: PTC

Interactor 2: HH (Q02936)
Protein hedgehog (EC 3.1.-.-) [Cleaved into: Protein hedgehog N-product (Hh-Np) (N-Hh)]
Gene: HH

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 20048000, 12783860, 16980583, unassigned4
Identification Methods affinity chromatography technology, experimental interaction detection
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HH_signal~Patched
Common GO terms GO:0001746 - Bolwig's organ morphogenesis
GO:0005886 - plasma membrane
GO:0007346 - regulation of mitotic cell cycle
GO:0007367 - segment polarity determination
GO:0007476 - imaginal disc-derived wing morphogenesis
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1286
Dm

1 471
+ Hs
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024