HitPredict

Interactor 1: EPOR (P19235)
Erythropoietin receptor (EPO-R)
Gene: EPOR

Interactor 2: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 9162069, 7559499, 15644415, 12506011, 24113870
Identification Methods affinity chromatography technology, protein complementation assay, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0019221 - cytokine-mediated signaling pathway
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 508
Hs

1 724
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024