Interactor 1: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1

Interactor 2: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP-eEF1A_C~GTP-eEF1A_C, GTP-eEF1A_C~GTP_EFTU, GTP-eEF1A_C~GTP_EFTU_D2, GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, GTP_EFTU_D2~GTP_EFTU_D2
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0003723 - RNA binding
GO:0003747 - translation release factor activity
GO:0003924 - GTPase activity
and 9 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 499
Hs

1 499
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Sc
+ Zm
+ Zm
+ Sc
+ Sc
+ Zm
+ Zm
+ Sp

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Last updated: 11Aug2025