HitPredict

Interactor 1: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Interactor 2: EF1A2 (Q05639)
Elongation factor 1-alpha 2 (EF-1-alpha-2) (EC 3.6.5.-) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1)
Gene: EEF1A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 33961781, 38334954, 31839598, 28514442, 35235311, 34349018, 35575683
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP-eEF1A_C~GTP-eEF1A_C, GTP-eEF1A_C~GTP_EFTU, GTP-eEF1A_C~GTP_EFTU_D2, GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, GTP_EFTU_D2~GTP_EFTU_D2
Common GO terms GO:0003746 - translation elongation factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005853 - eukaryotic translation elongation factor 1 complex
and 5 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 462
Hs

1 463
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Service provided by Combinatics, Japan

Last updated: 11Aug2025