HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: TBA1B (Q6P9V9)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin 2) (Tubulin alpha-2 chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: Tuba1b

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0015630 - microtubule cytoskeleton GO:0045121 - membrane raft
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 752 Rn			1 451
+	Rn
		94246 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		TBA1B_RAT (1-440): 0: 717: 100.00
+	Mm
		399082 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		TBA1B_MOUSE (1-440): 0: 717: 100.00
+	Mm
		498002 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		TBA1A_MOUSE (1-440): 0: 715: 99.55
+	Hs
		497515 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TBA1C_HUMAN (1-451): 0: 728: 98.00
+	Mm
		498012 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		TBB5_MOUSE (1-439): 0: 699: 41.23
+	Hs
		496818 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		496817 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		497220 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		497683 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TBA8_HUMAN (1-440): 0: 701: 90.68
+	Hs
		427983 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		496819 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		653957 MAP4_HUMAN (9-727): 1.28e-34: 144: 19.84		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		503294 MTAP2_HUMAN (42-752): 4.53e-33: 139: 24.66		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		965128 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428145 ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Mm
		649204 MAP4_MOUSE (4-752): 3.57e-18: 91.6: 15.47		TBA1A_MOUSE (1-440): 0: 715: 99.55
+	Hs
		92120 NACAM_HUMAN (15-750): 9.02e-17: 87.4: 8.41		TBA1A_HUMAN (1-440): 0: 715: 99.55