HitPredict

Interactor 1: CSK22 (P19454)
Casein kinase II subunit alpha' (CK II) (EC 2.7.11.1)
Gene: CKA2

Interactor 2: IFH1 (P39520)
Protein IFH1 (Ribosomal RNA-processing protein 3)
Gene: IFH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	27321754, 37968396, 27818142, 16429126
Identification Methods	enzymatic study, affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0032545 - CURI complex GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I GO:0060962 - regulation of ribosomal protein gene transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 339 Sc			1 1085
+	Sc
		550040 CSK21_YEAST (14-334): 3.73e-104: 311: 50.55		IFH1_YEAST (1-1085): 0: 645: 100.00
+	Hs
		625177 CDK2_HUMAN (47-335): 6.33e-123: 356: 27.67		MYH10_HUMAN (54-901): 9.76e-61: 230: 13.73
+	Hs
		835653 GSK3B_HUMAN (4-339): 3.77e-117: 346: 26.78		MAP1A_HUMAN (33-568): 8.63e-51: 198: 11.99
+	Hs
		724768 CSK21_HUMAN (12-334): 5.32e-122: 357: 59.26		MYH9_HUMAN (56-901): 1.25e-41: 169: 11.35
+	Hs
		625176 CDK2_HUMAN (47-335): 6.33e-123: 356: 27.67		MYH9_HUMAN (56-901): 1.25e-41: 169: 11.35
+	Sc
		584795 CSK22_YEAST (1-339): 5.38e-120: 350: 100.00		CRF1_YEAST (377-792): 5.28e-45: 171: 21.58
+	Hs
		724714 GSK3B_HUMAN (4-339): 3.77e-117: 346: 26.78		MYH9_HUMAN (56-901): 1.25e-41: 169: 11.35
+	Hs
		835321 GSK3A_HUMAN (2-334): 5.19e-104: 315: 30.23		MAP1A_HUMAN (33-568): 8.63e-51: 198: 11.99
+	Hs
		835536 GSK3A_HUMAN (2-334): 5.19e-104: 315: 30.23		MDN1_HUMAN (63-673): 1.16e-26: 120: 11.50
+	Hs
		625530 CDK2_HUMAN (47-335): 6.33e-123: 356: 27.67		MY18A_HUMAN (60-624): 5.97e-12: 72.3: 10.86