Interactor 1: E2AK2 (P19525)
Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)
Gene: EIF2AK2
Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21903422 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Helicase_C~dsrm, Ribonuclease_3~dsrm |
| Common GO terms | GO:0003723 - RNA binding GO:0003725 - double-stranded RNA binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm and 2 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
