HitPredict

Interactor 1: PHKG2 (P15735)
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2)
Gene: PHKG2

Interactor 2: KPBB (Q93100)
Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta)
Gene: PHKB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.967

Property	Details
Experiments	26496610, 28514442, 33961781, 35271311, 32707033, 36736316, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Glyco_hydro_15~Pkinase
Common GO terms	GO:0005516 - calmodulin binding GO:0005829 - cytosol GO:0005964 - phosphorylase kinase complex GO:0005977 - glycogen metabolic process GO:0006091 - generation of precursor metabolites and energy
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 1093
+	Hs
		1110524 KCC2D_HUMAN (20-306): 5.52e-63: 212: 39.86		KPBB_HUMAN (1-1093): 0: 1786: 100.00
+	Hs
		1110387 KCC2G_HUMAN (15-306): 1.32e-61: 209: 39.39		KPBB_HUMAN (1-1093): 0: 1786: 100.00
+	Hs
		1110283 KCC2B_HUMAN (20-306): 2e-59: 206: 39.86		KPBB_HUMAN (1-1093): 0: 1786: 100.00
+	Dm
		1379321 Q961E7_DROME (1-389): 2.83e-134: 392: 50.60		KPBB_DROME (29-1088): 0: 1509: 46.88
+	Dm
		1379327 Q961E7_DROME (1-389): 2.83e-134: 392: 50.60		KPBA_DROME (691-1077): 1.16e-144: 468: 28.45
+	Hs
		585772 PHKG2_HUMAN (1-406): 5.5e-154: 442: 100.00		KPB2_HUMAN (912-1086): 1.15e-58: 223: 35.36
+	Hs
		585773 PHKG2_HUMAN (1-406): 5.5e-154: 442: 100.00		KPB1_HUMAN (930-1079): 5.75e-52: 201: 32.48
+	Hs
		854438 PHKG1_HUMAN (5-389): 1.36e-139: 405: 62.44		KPB2_HUMAN (912-1086): 1.15e-58: 223: 35.36