HitPredict

Interactor 1: FEM1B (A1ZBY1)
Protein fem-1 homolog B (dFEM-1)
Gene: Fem-1

Interactor 2: O96692 (O96692)
small monomeric GTPase (EC 3.6.5.2)
Gene: Rap2l

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 650 Dm			1 182
+	Mm
		74667 ANR44_MOUSE (292-645): 4.56e-32: 134: 11.83		RAB13_MOUSE (4-178): 9.45e-73: 219: 29.55
+	Hs
		920420 DAPK1_HUMAN (3-143): 7.84e-19: 93.6: 22.70		RB11A_HUMAN (4-176): 1.49e-74: 224: 32.76
+	Hs
		956539 KDIS_HUMAN (230-597): 8.8e-18: 90.2: 12.23		RAB2A_HUMAN (4-170): 1.12e-75: 227: 33.93
+	Hs
		976655 KDIS_HUMAN (230-597): 8.8e-18: 90.2: 12.23		RB11A_HUMAN (4-176): 1.49e-74: 224: 32.76
+	Hs
		374276 ANR50_HUMAN (428-649): 6.26e-33: 138: 9.47		RASN_HUMAN (1-174): 8.4e-45: 148: 47.13
+	Hs
		376087 ANR50_HUMAN (428-649): 6.26e-33: 138: 9.47		RASK_HUMAN (1-181): 1.2e-44: 147: 44.57
+	Dm
		68588 A8JNM5_DROME (286-647): 4.16e-31: 132: 8.56		RALA_DROME (5-182): 1.05e-46: 153: 42.33
+	Dm
		1343481 Q8SWY2_DROME (443-647): 2.91e-27: 119: 13.17		Q962I2_DROME (5-182): 2.32e-49: 159: 43.24
+	Hs
		375418 ANK2_HUMAN (456-650): 4.19e-28: 123: 13.78		RASK_HUMAN (1-181): 1.2e-44: 147: 44.57
+	Hs
		375464 ANK3_HUMAN (517-648): 5.92e-21: 100: 10.61		RASK_HUMAN (1-181): 1.2e-44: 147: 44.57
+	Hs
		374275 KDIS_HUMAN (230-597): 8.8e-18: 90.2: 12.23		RASN_HUMAN (1-174): 8.4e-45: 148: 47.13
+	Hs
		376086 KDIS_HUMAN (230-597): 8.8e-18: 90.2: 12.23		RASK_HUMAN (1-181): 1.2e-44: 147: 44.57