HitPredict

Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: IFNL1 (Q8IU54)
Interferon lambda-1 (IFN-lambda-1) (Cytokine Zcyto21) (Interleukin-29) (IL-29)
Gene: IFNL1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17785777, 17204473
Identification Methods	affinity chromatography technology, electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0045087 - innate immune response GO:0045893 - positive regulation of DNA-templated transcription GO:0098586 - cellular response to virus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 968 Hs			1 200
+	Hs
		587630 NFKB1_HUMAN (1-968): 0: 796: 100.00		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		964497 RELB_HUMAN (30-459): 1.19e-121: 384: 33.10		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		978798 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		964498 RELB_HUMAN (30-459): 1.19e-121: 384: 33.10		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		978803 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		961403 NFKB2_HUMAN (701-942): 4.27e-26: 117: 14.23		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		961404 NFKB2_HUMAN (701-942): 4.27e-26: 117: 14.23		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94