HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: BRE1A (Q5VTR2)
E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A)
Gene: RNF20

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	37155876
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 975
+	Hs
		272611 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		BRE1B_HUMAN (1-974): 2.16e-60: 225: 56.09
+	Hs
		270768 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		ROCK2_HUMAN (96-897): 2.16e-15: 83.5: 14.08
+	Hs
		588059 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		MYH11_HUMAN (561-933): 5.95e-14: 79: 10.46
+	Hs
		588049 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		MYH9_HUMAN (561-959): 1.37e-13: 77.5: 9.59
+	Hs
		588050 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		MYH10_HUMAN (1-355): 1.6e-13: 77.5: 9.47
+	Hs
		587545 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		DESP_HUMAN (225-919): 9.05e-12: 71.9: 16.12
+	Hs
		589299 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		MY18A_HUMAN (326-919): 1.43e-10: 67.7: 15.69
+	Hs
		589537 RFA2_HUMAN (1-270): 1.69e-127: 364: 100.00		FYCO1_HUMAN (70-921): 5.81e-09: 62.3: 14.87