Interactor 1: TBP (P20227)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: Q9VEL2 (Q9VEL2)
B-related factor 1
Gene: Brf

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 25242320, 37061542, unassigned1513
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BRF1~TBP, TBP~TFIIB
Common GO terms GO:0000126 - transcription factor TFIIIB complex
GO:0000995 - RNA polymerase III general transcription initiation factor activity
GO:0001006 - RNA polymerase III type 3 promoter sequence-specific DNA binding
GO:0005634 - nucleus
GO:0006352 - DNA-templated transcription initiation
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 353
Dm

1 662
+ Dm
+ Hs
+ Sc
+ Dm
+ Sp
+ Mm
+ Hs
+ Dm
+ Sc
+ Hs
+ Hs
+ At
+ Pf

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Last updated: 15 Jul 2024