HitPredict

Interactor 1: RAB3A (P20336)
Ras-related protein Rab-3A
Gene: RAB3A

Interactor 2: RAE2 (P26374)
Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2)
Gene: CHML

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.899

Property	Details
Experiments	8294464, 26186194, 28514442, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Hs			1 656
+	Hs
		591507 RAB3B_HUMAN (1-220): 2.99e-92: 271: 77.73		RAE2_HUMAN (1-656): 0: 980: 100.00
+	Hs
		642723 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		RAE2_HUMAN (1-656): 0: 980: 100.00
+	Hs
		642718 RAB8A_HUMAN (15-218): 1.04e-87: 259: 48.53		RAE2_HUMAN (1-656): 0: 980: 100.00
+	Hs
		642743 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		RAE2_HUMAN (1-656): 0: 980: 100.00
+	Hs
		622577 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		RAE1_HUMAN (1-652): 0: 946: 71.98
+	Hs
		591450 RAB3A_HUMAN (1-220): 5.84e-88: 260: 100.00		RAE1_HUMAN (1-652): 0: 946: 71.98
+	Hs
		622570 RAB8A_HUMAN (15-218): 1.04e-87: 259: 48.53		RAE1_HUMAN (1-652): 0: 946: 71.98
+	Hs
		622619 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		RAE1_HUMAN (1-652): 0: 946: 71.98
+	Hs
		591514 RAB3B_HUMAN (1-220): 2.99e-92: 271: 77.73		GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49
+	Dm
		627447 RAB3_DROME (1-220): 9.14e-94: 275: 76.47		Q9VLB7_DROME (176-547): 7.18e-140: 417: 23.75
+	Mm
		838709 RAB1A_MOUSE (12-220): 2.68e-90: 265: 44.02		GDIA_MOUSE (167-599): 1.13e-141: 422: 20.49
+	Hs
		678344 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49
+	Hs
		838625 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52
+	Mm
		838710 RAB3A_MOUSE (1-220): 3.77e-88: 260: 99.09		GDIA_MOUSE (167-599): 1.13e-141: 422: 20.49
+	Hs
		591453 RAB3A_HUMAN (1-220): 5.84e-88: 260: 100.00		GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49
+	Hs
		678336 RAB8A_HUMAN (15-218): 1.04e-87: 259: 48.53		GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49
+	Hs
		678394 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49
+	Hs
		591462 RAB3A_HUMAN (1-220): 5.84e-88: 260: 100.00		GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52
+	Hs
		838616 RAB8A_HUMAN (15-218): 1.04e-87: 259: 48.53		GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52
+	Hs
		838683 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52