HitPredict

Interactor 1: GROU (P16371)
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)
Gene: gro

Interactor 2: Q9N693 (Q9N693)
Brakeless-B (Scribbler long isoform) (Scribbler, isoform D) (Scribbler, isoform H)
Gene: sbb

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17571073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 730 Dm			1 2302
+	Dm
		594703 GROU_DROME (1-730): 7.6e-174: 517: 100.00		Q9GRA9_DROME (7-2302): 1.69e-161: 556: 99.65
+	Hs
		174342 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		ZN609_HUMAN (654-2015): 3.9e-42: 172: 17.16
+	Hs
		1048129 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		ZN608_HUMAN (739-1206): 1.12e-35: 151: 30.87
+	Hs
		1048137 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		SRRM2_HUMAN (584-2175): 1.82e-21: 105: 9.21
+	Hs
		1047877 TLE1_HUMAN (1-730): 2.45e-154: 468: 59.95		RERE_HUMAN (739-1723): 2.72e-13: 78.3: 8.63
+	Hs
		1048052 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		CBP_HUMAN (1197-1847): 3e-17: 91.6: 14.79
+	Hs
		1048118 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		RERE_HUMAN (739-1723): 2.72e-13: 78.3: 8.63
+	Hs
		1048072 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		MINT_HUMAN (922-2017): 5.56e-10: 67.3: 9.14
+	Hs
		1061746 TLE5_HUMAN (1-197): 4.9e-83: 263: 49.51		ANR11_HUMAN (1402-2154): 3.88e-09: 64.6: 11.33
+	Hs
		174387 SNR40_HUMAN (382-602): 6.03e-28: 118: 16.67		ZN609_HUMAN (654-2015): 3.9e-42: 172: 17.16
+	Hs
		992751 RACK1_HUMAN (525-728): 1.23e-53: 189: 20.83		MDC1_HUMAN (1409-2231): 8.32e-15: 83.5: 9.56
+	Hs
		1387633 SNR40_HUMAN (382-602): 6.03e-28: 118: 16.67		ZN608_HUMAN (739-1206): 1.12e-35: 151: 30.87
+	Hs
		1450952 NLE1_HUMAN (615-729): 3.95e-34: 138: 17.89		SRRM2_HUMAN (584-2175): 1.82e-21: 105: 9.21
+	Hs
		845363 LIS1_HUMAN (603-728): 1.46e-32: 132: 21.09		SRRM2_HUMAN (584-2175): 1.82e-21: 105: 9.21
+	Hs
		1387648 SNR40_HUMAN (382-602): 6.03e-28: 118: 16.67		SRRM2_HUMAN (584-2175): 1.82e-21: 105: 9.21
+	Hs
		1403515 NLE1_HUMAN (615-729): 3.95e-34: 138: 17.89		MINT_HUMAN (922-2017): 5.56e-10: 67.3: 9.14
+	Hs
		1129693 SNR40_HUMAN (382-602): 6.03e-28: 118: 16.67		MDC1_HUMAN (1409-2231): 8.32e-15: 83.5: 9.56
+	Hs
		1387512 SNR40_HUMAN (382-602): 6.03e-28: 118: 16.67		MINT_HUMAN (922-2017): 5.56e-10: 67.3: 9.14
+	Dm
		119661 GBLP_DROME (615-729): 1.87e-22: 100: 18.55		M9PB30_DROME (1852-2302): 1.33e-13: 79.4: 11.04
+	Mm
		965395 WDR5_MOUSE (316-470): 1.17e-13: 74.9: 7.98		KMT2C_MOUSE (1296-2225): 2.62e-19: 98.5: 12.73