HitPredict

Interactor 1: CD11B (P21127)
Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)
Gene: CDK11B

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	15883043
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 795 Hs			1 246
+	Hs
		596736 CD11B_HUMAN (1-795): 0: 574: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		596738 CD11B_HUMAN (1-795): 0: 574: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		910170 CD11A_HUMAN (1-795): 0: 561: 96.86		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		596718 CD11B_HUMAN (1-795): 0: 574: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		596735 CD11B_HUMAN (1-795): 0: 574: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		625306 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		625334 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		909447 CDK3_HUMAN (435-731): 8.54e-148: 436: 45.64		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683268 CDK3_HUMAN (435-731): 8.54e-148: 436: 45.64		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		625130 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	At
		965298 MPK7_ARATH (413-762): 1.26e-135: 408: 28.81		14332_ARATH (1-241): 4.75e-145: 407: 63.27
+	Hs
		646799 CDK3_HUMAN (435-731): 8.54e-148: 436: 45.64		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		625296 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		625383 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		960082 CDK3_HUMAN (435-731): 8.54e-148: 436: 45.64		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		683964 CDK3_HUMAN (435-731): 8.54e-148: 436: 45.64		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		414774 CDK1_HUMAN (435-726): 7.24e-138: 411: 41.84		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		683213 CDK7_HUMAN (436-760): 1.13e-72: 243: 38.69		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		646734 CDK7_HUMAN (436-760): 1.13e-72: 243: 38.69		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		841128 CDK7_HUMAN (436-760): 1.13e-72: 243: 38.69		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40