HitPredict

Interactor 1: TNAP3 (P21580)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]
Gene: TNFAIP3

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.763

The method score is based on:

Property Details
Experiments 30561431, 35099607, 36574265, 25165885, 25416956, 32296183, 10385526, 34839354, 18029035, 11389905, 12586352, 21988832, 16684768, 31515488, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, virotrap, two hybrid prey pooling approach, two hybrid array, validated two hybrid, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0043124 - negative regulation of canonical NF-kappaB signal transduction
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 790
Hs

1 636
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024