Interactor 1: RU17 (P17133)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: snRNP-U1-70K

Interactor 2: PUF68 (Q8T6B9)
Poly(U)-binding-splicing factor hfp (68 kDa poly(U)-binding-splicing factor) (PUF60 homolog) (Protein half pint)
Gene: hfp

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1, RRM_1~U1snRNP70_N
Common GO terms GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0048477 - oogenesis
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 448
Dm

1 637
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025