HitPredict

Interactor 1: DPOE (P21951)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POL2

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	23332755, 19536198
Identification Methods	biochemical, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2222 Sc			1 613
+	Sc
		510261 DPOE_YEAST (1-2222): 0: 2941: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		503958 DPOE1_HUMAN (7-2218): 0: 2923: 39.43		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		548483 DPOD_YEAST (26-637): 1.17e-127: 433: 14.29		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510136 DPOD_YEAST (26-637): 1.17e-127: 433: 14.29		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		536236 DPOZ_YEAST (32-649): 4.39e-104: 371: 11.30		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510108 DPOZ_YEAST (32-649): 4.39e-104: 371: 11.30		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		526848 DPOLA_YEAST (231-637): 1.77e-77: 287: 10.92		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510090 DPOLA_YEAST (231-637): 1.77e-77: 287: 10.92		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		503495 DPOD1_HUMAN (1-637): 3.42e-144: 481: 14.67		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Sc
		449887 DPOD_YEAST (26-637): 1.17e-127: 433: 14.29		HSP73_YEAST (9-611): 0: 677: 60.66