HitPredict

Interactor 1: MDHM (P17505)
Malate dehydrogenase, mitochondrial (EC 1.1.1.37)
Gene: MDH1

Interactor 2: ACON (P19414)
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)
Gene: ACO1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	37968396, 31548421, 32051233
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0006099 - tricarboxylic acid cycle
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 334 Sc			1 778
+	Mm
		469625 MDHM_MOUSE (3-333): 7.1e-125: 363: 51.51		ACON_MOUSE (9-777): 0: 1003: 67.10
+	Dm
		1472464 Q9VEB1_DROME (8-332): 7.96e-128: 370: 51.23		Q9VIE8_DROME (2-777): 0: 993: 66.37
+	Hs
		828912 MDHM_HUMAN (3-333): 3.38e-123: 358: 53.31		ACON_HUMAN (9-777): 0: 995: 66.71
+	Sc
		604965 MDHM_YEAST (1-334): 7.62e-126: 365: 100.00		LYS4_YEAST (57-729): 4.13e-167: 500: 24.20