Interactor 1: IL10 (P22301)
Interleukin-10 (IL-10) (Cytokine synthesis inhibitory factor) (CSIF)
Gene: IL10

Interactor 2: IL10 (P22301)
Interleukin-10 (IL-10) (Cytokine synthesis inhibitory factor) (CSIF)
Gene: IL10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.90 0.738

The method score is based on:

Property Details
Experiments 8590020, 12513909
Identification Methods x-ray crystallography, molecular sieving
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL10~IL10
Common GO terms GO:0001818 - negative regulation of cytokine production
GO:0001819 - positive regulation of cytokine production
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002237 - response to molecule of bacterial origin
GO:0002439 - chronic inflammatory response to antigenic stimulus
and 71 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024