HitPredict

Interactor 1: IDS (P22304)
Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain]
Gene: IDS

Interactor 2: MESD (Q14696)
LRP chaperone MESD (LDLR chaperone MESD) (Mesoderm development LRP chaperone MESD) (Mesoderm development candidate 2) (Mesoderm development protein) (Renal carcinoma antigen NY-REN-61)
Gene: MESD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 234
+	Hs
		1058353 ARSK_HUMAN (25-536): 6.99e-104: 324: 19.96		MESD_HUMAN (1-234): 1.2e-119: 341: 100.00
+	Hs
		709250 GALNS_HUMAN (12-436): 8.93e-95: 300: 21.68		MESD_HUMAN (1-234): 1.2e-119: 341: 100.00
+	Hs
		546613 ARSA_HUMAN (35-467): 7.03e-93: 295: 19.52		MESD_HUMAN (1-234): 1.2e-119: 341: 100.00
+	Hs
		1058382 ARSG_HUMAN (29-437): 7.93e-81: 264: 19.30		MESD_HUMAN (1-234): 1.2e-119: 341: 100.00