HitPredict

Interactor 1: MYD88 (P22366)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: TRAF3 (Q60803)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.670

The method score is based on:

Property Details
Experiments 19898473, 16306937, 22011580
Identification Methods pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0008063 - Toll signaling pathway
GO:0032481 - positive regulation of type I interferon production
GO:0034142 - toll-like receptor 4 signaling pathway
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 296
Mm

1 567
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024