Interactor 1: PDI (P17967)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Thioredoxin-related glycoprotein 1)
Gene: PDI1
Interactor 2: MNL1 (P38888)
ER degradation-enhancing alpha-mannosidase-like protein 1 (EC 3.2.1.24)
Gene: MNL1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.974 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27053108, 19124653, 35084835, 19279007, 16554755, 27357682, 39930008, 16429126 |
| Identification Methods | affinity chromatography technology, pull down, x-ray crystallography, biochemical, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Glyco_hydro_47~Thioredoxin |
| Common GO terms | GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0106055 - mannosyl-oligosaccharide 1,2-alpha-mannosidase complex GO:1900103 - positive regulation of endoplasmic reticulum unfolded protein response |
| Homologous interactions | 12 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
