HitPredict

Interactor 1: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: H2AJ (Q9BTM1)
Histone H2A.J (H2a/j)
Gene: H2AJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36470425
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 906 Hs			1 129
+	Hs
		610423 CBL_HUMAN (1-906): 0: 917: 100.00		H2A2C_HUMAN (1-129): 1.07e-66: 199: 96.90
+	Hs
		610493 CBL_HUMAN (1-906): 0: 917: 100.00		H2A1J_HUMAN (1-127): 6.97e-66: 197: 95.28
+	Hs
		610436 CBL_HUMAN (1-906): 0: 917: 100.00		H2A2A_HUMAN (1-127): 2.77e-65: 196: 95.28
+	Hs
		610480 CBL_HUMAN (1-906): 0: 917: 100.00		H2A1H_HUMAN (1-127): 1.69e-65: 196: 95.28
+	Hs
		470269 CBL_HUMAN (1-906): 0: 917: 100.00		H2A1_HUMAN (1-127): 4.34e-65: 195: 95.28
+	Hs
		554260 MUC1_HUMAN (449-906): 3.82e-14: 79.2: 10.58		H2AX_HUMAN (1-124): 3.04e-64: 193: 94.36
+	Hs
		391802 KMT2C_HUMAN (411-860): 1.11e-13: 78: 11.93		H2A1B_HUMAN (1-127): 7.27e-65: 194: 93.70
+	Hs
		555463 MDC1_HUMAN (450-878): 1.89e-11: 70.3: 9.33		H2AX_HUMAN (1-124): 3.04e-64: 193: 94.36
+	Mm
		101453 F8VPR5_MOUSE (419-840): 3.09e-10: 66.5: 7.89		H2A3_MOUSE (1-127): 4.74e-65: 195: 94.49
+	Hs
		1273164 PRG4_HUMAN (480-830): 5.07e-09: 62.6: 12.39		H2A1H_HUMAN (1-127): 1.69e-65: 196: 95.28