HitPredict

Interactor 1: PSA4 (P18053)
Proteasome subunit alpha type-4 (PROS-Dm29) (Proteasome 29 kDa subunit)
Gene: Prosalpha3

Interactor 2: Q9W414 (Q9W414)
Regulatory particle triple-A ATPase 4 (EC 5.6.1.5)
Gene: Rpt4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~Proteasome, AAA_lid_3~Proteasome, AAA~Proteasome_A_N, AAA_lid_3~Proteasome_A_N
Common GO terms GO:0005634 - nucleus
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 264
Dm

1 397
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025