HitPredict

Interactor 1: SYB (P18489)
Synaptobrevin
Gene: SYB

Interactor 2: Q9W0N6 (Q9W0N6)
LD27967p (Vesicle transport through interaction with t-SNAREs 1a)
Gene: Vti1a

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Synaptobrevin~V-SNARE_C
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0006906 - vesicle fusion GO:0016192 - vesicle-mediated transport GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Dm			1 230
+	Dm
		614955 SYB_DROME (1-152): 1.12e-53: 168: 100.00		GOSR2_DROME (4-218): 1.17e-49: 163: 18.52
+	Dm
		1263478 Q7JYX5_DROME (4-127): 3.99e-39: 133: 14.29		Q9W0N6_DROME (1-225): 9.61e-59: 186: 100.00
+	Dm
		121835 M9PGI6_DROME (3-128): 8.27e-37: 127: 16.67		Q9W0N6_DROME (1-225): 9.61e-59: 186: 100.00
+	Rn
		204395 SC22B_RAT (3-131): 5.15e-39: 132: 18.32		GOSR2_RAT (4-218): 1.01e-54: 176: 17.67
+	At
		235609 VA711_ARATH (3-130): 4.22e-36: 125: 18.46		VTI11_ARATH (2-221): 4.07e-57: 182: 28.64
+	Hs
		160229 SC22B_HUMAN (3-131): 5.15e-39: 132: 18.32		GOSR2_HUMAN (4-218): 1.04e-53: 173: 16.74
+	Hs
		280297 SC22B_HUMAN (3-131): 5.15e-39: 132: 18.32		VTI1A_HUMAN (2-218): 9.87e-54: 173: 36.41
+	Dm
		1263469 Q7JYX5_DROME (4-127): 3.99e-39: 133: 14.29		GOSR2_DROME (4-218): 1.17e-49: 163: 18.52
+	Dm
		121827 M9PGI6_DROME (3-128): 8.27e-37: 127: 16.67		GOSR2_DROME (4-218): 1.17e-49: 163: 18.52
+	Dm
		305592 O77434_DROME (3-128): 9.32e-37: 127: 16.67		GOSR2_DROME (4-218): 1.17e-49: 163: 18.52
+	Rn
		1224615 VAMP1_RAT (18-120): 1.45e-31: 110: 56.31		VTI1A_RAT (2-219): 2.67e-55: 178: 35.62
+	Hs
		280365 SC22B_HUMAN (3-131): 5.15e-39: 132: 18.32		VTI1B_HUMAN (2-220): 8.06e-45: 151: 22.97
+	Mm
		312202 VAMP7_MOUSE (3-112): 5.31e-31: 112: 22.32		VTI1B_MOUSE (2-220): 2.44e-51: 168: 23.87
+	Hs
		908061 VAMP7_HUMAN (3-112): 4.71e-31: 112: 22.32		VTI1B_HUMAN (2-220): 8.06e-45: 151: 22.97
+	Sc
		646266 SEC22_YEAST (3-129): 6.21e-37: 127: 19.38		VTI1_YEAST (2-202): 9.46e-36: 127: 28.57
+	Dm
		84843 SYB_DROME (1-152): 1.12e-53: 168: 100.00		B7Z0M0_DROME (111-221): 2.08e-17: 77.1: 25.23
+	Sc
		751602 SNC2_YEAST (18-115): 5.49e-29: 104: 29.59		VTI1_YEAST (2-202): 9.46e-36: 127: 28.57
+	Dm
		84855 Q7JYX5_DROME (4-127): 3.99e-39: 133: 14.29		B7Z0M0_DROME (111-221): 2.08e-17: 77.1: 25.23
+	Dm
		84840 O77434_DROME (3-128): 9.32e-37: 127: 16.67		B7Z0M0_DROME (111-221): 2.08e-17: 77.1: 25.23
+	Dm
		84890 NSYB_DROME (37-130): 1.25e-31: 113: 68.09		B7Z0M0_DROME (111-221): 2.08e-17: 77.1: 25.23