HitPredict - High confidence protein-protein interactions

Interactor 1: RS3 (P23396)
Small ribosomal subunit protein uS3 (40S ribosomal protein S3) (EC 4.2.99.18)
Gene: RPS3

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	18045535, 23188828, 14743216, 26526615, 24457201
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 10 others more... GO:0010628 - positive regulation of gene expression GO:0019899 - enzyme binding GO:0019901 - protein kinase binding GO:0050862 - positive regulation of T cell receptor signaling pathway GO:0051092 - positive regulation of NF-kappaB transcription factor activity GO:0070301 - cellular response to hydrogen peroxide GO:0071159 - NF-kappaB complex GO:0071356 - cellular response to tumor necrosis factor GO:0140297 - DNA-binding transcription factor binding GO:1901224 - positive regulation of non-canonical NF-kappaB signal transduction
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	243
Hs

1	551

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Last updated: 15 Jul 2024