Protein: RCC1
Guanine nucleotide exchange factor SRM1 (Pheromone response pathway component SRM1) (Pre-mRNA-processing protein 20) (Regulator of chromosome condensation) (Suppressor of receptor mutations 1) (mRNA transport protein 1)

Gene: RCC1, SRM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: P21827

Gene Ontology (top 5):
GO:0000054 - ribosomal subunit export from nucleus
GO:0000785 - chromatin
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

641422

GSP1
GTP-binding nuclear protein GSP1/CNR1

10

6

Small-scale

0.753

High

641442

H3
Histone H3

3

6

Small-scale

0.646

High

641419

NUP2
Nucleoporin NUP2

2

13

Small-scale

0.624

High

381870

H4
Histone H4

2

2

Small-scale

0.595

High

419355

H2A1
Histone H2A.1

2

5

Small-scale

0.595

High

419595

H2A2
Histone H2A.2

2

5

Small-scale

0.595

High

641452

SCC1
Sister chromatid cohesion protein 1

2

0

High-throughput

0.585

High

641423

GSP2
GTP-binding nuclear protein GSP2/CNR2

2

6

Small-scale

0.584

High

641415

SIS1
Protein SIS1

2

4

High-throughput

0.571

High

364329

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.537

High

641444

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

1

High-throughput

0.515

High

454398

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

641417

XPO1
Exportin-1

1

7

Small-scale

0.508

High

641435

YRB1
Ran-specific GTPase-activating protein 1

1

10

Small-scale

0.508

High

641426

BOI1
BEM1-interacting protein 1

1

6

High-throughput

0.501

High

641445

IMA1
Importin subunit alpha

1

2

Small-scale

0.501

High

641449

RRP44
Exosome complex exonuclease DIS3

1

1

Small-scale

0.501

High

641439

SYC
Cysteine--tRNA ligase

1

0

High-throughput

0.493

High

641443

RAGAB
GTP-binding protein GTR1

1

0

Small-scale

0.480

High

380965

H2B1
Histone H2B.1

1

5

Small-scale

0.479

High

381398

H2B2
Histone H2B.2

1

5

Small-scale

0.479

High

448282

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

2

High-throughput

0.479

High

560229

TOP3
DNA topoisomerase 3

1

2

High-throughput

0.479

High

578848

HSC82
ATP-dependent molecular chaperone HSC82

1

13

High-throughput

0.479

High

641420

SPT16
FACT complex subunit SPT16

1

1

Small-scale

0.479

High

641427

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

2

High-throughput

0.479

High

641429

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

2

High-throughput

0.479

High

641431

IMB4
Importin subunit beta-4

1

1

Small-scale

0.479

High

641433

ATAD2
ATPase histone chaperone YTA7

1

3

High-throughput

0.479

High

641434

YRB2
Ran-specific GTPase-activating protein 2

1

10

Small-scale

0.479

High

641440

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.479

High

641441

ACT
Actin

1

3

Small-scale

0.479

High

641446

RUVB1
RuvB-like protein 1

1

3

Small-scale

0.479

High

641447

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.479

High

641450

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

4

Small-scale

0.479

High

641453

RUVB2
RuvB-like protein 2

1

3

Small-scale

0.479

High

641454

H2AZ
Histone H2A.Z

1

5

Small-scale

0.479

High

558583

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

594185

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

641414

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

641416

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

641418

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

641425

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

641436

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

Small-scale

0.458

High

641437

ITC1
Imitation switch two complex protein 1

1

0

Small-scale

0.458

High

641438

H1
Histone H1

1

0

Small-scale

0.458

High

641448

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

641451

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

543816

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

641421

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

641430

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.445

High

641432

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

641424

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

641428

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025