HitPredict

Interactor 1: PTPRZ (P23471)
Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2)
Gene: PTPRZ1

Interactor 2: PTPRZ (P23471)
Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2)
Gene: PTPRZ1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.49 1.00 0.701

The method score is based on:

Property Details
Experiments 18838383, 15978577
Identification Methods biochemical, tox-r dimerization assay
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Carb_anhydrase~Carb_anhydrase, fn3~fn3, Y_phosphatase~Y_phosphatase
Common GO terms GO:0002244 - hematopoietic progenitor cell differentiation
GO:0004725 - protein tyrosine phosphatase activity
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005178 - integrin binding
GO:0005576 - extracellular region
and 13 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 2315
Hs

1 2315
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Last updated: 15 Jul 2024