HitPredict

Interactor 1: CDC42 (P19073)
Cell division control protein 42 (EC 3.6.5.2) (Suppressor of RHO3 protein 2)
Gene: CDC42

Interactor 2: RGD2 (P43556)
Rho-GTPase-activating protein RGD2
Gene: RGD2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	11591390
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005934 - cellular bud tip GO:0005935 - cellular bud neck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Sc			1 714
+	Hs
		988825 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		PACN2_HUMAN (5-403): 6.14e-97: 309: 15.11
+	Hs
		1015904 RHOG_HUMAN (1-191): 9.03e-81: 240: 58.64		PACN2_HUMAN (5-403): 6.14e-97: 309: 15.11
+	Hs
		1433578 RHOJ_HUMAN (2-189): 4.78e-79: 236: 59.04		PACN2_HUMAN (5-403): 6.14e-97: 309: 15.11
+	Hs
		988810 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		PACN3_HUMAN (4-403): 9.19e-87: 281: 14.29
+	Hs
		1433571 RHOJ_HUMAN (2-189): 4.78e-79: 236: 59.04		PACN3_HUMAN (4-403): 9.19e-87: 281: 14.29
+	Hs
		1150892 RHOJ_HUMAN (2-189): 4.78e-79: 236: 59.04		CIP4_HUMAN (9-390): 1.86e-59: 212: 14.76
+	Hs
		955197 CDC42_HUMAN (1-191): 1.47e-79: 236: 80.11		CIP4_HUMAN (9-390): 1.86e-59: 212: 14.76
+	Hs
		988631 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		FNBP1_HUMAN (9-288): 1.16e-56: 205: 13.29
+	Hs
		1015698 RHOG_HUMAN (1-191): 9.03e-81: 240: 58.64		FNBP1_HUMAN (9-288): 1.16e-56: 205: 13.29
+	Hs
		1402034 RHOJ_HUMAN (2-189): 4.78e-79: 236: 59.04		FNBP1_HUMAN (9-288): 1.16e-56: 205: 13.29
+	Hs
		955501 CDC42_HUMAN (1-191): 1.47e-79: 236: 80.11		FNBP1_HUMAN (9-288): 1.16e-56: 205: 13.29
+	Hs
		988427 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		FBP1L_HUMAN (9-226): 1.03e-51: 191: 14.80
+	Hs
		1211652 RHOJ_HUMAN (2-189): 4.78e-79: 236: 59.04		FBP1L_HUMAN (9-226): 1.03e-51: 191: 14.80
+	Hs
		955266 CDC42_HUMAN (1-191): 1.47e-79: 236: 80.11		FBP1L_HUMAN (9-226): 1.03e-51: 191: 14.80
+	Hs
		988316 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		FCHO2_HUMAN (1-236): 1.92e-46: 178: 15.06
+	Hs
		1015391 RHOG_HUMAN (1-191): 9.03e-81: 240: 58.64		FCHO2_HUMAN (1-236): 1.92e-46: 178: 15.06
+	Hs
		1070514 RHOJ_HUMAN (2-189): 4.78e-79: 236: 59.04		FCHO2_HUMAN (1-236): 1.92e-46: 178: 15.06
+	Hs
		955098 CDC42_HUMAN (1-191): 1.47e-79: 236: 80.11		FCHO2_HUMAN (1-236): 1.92e-46: 178: 15.06
+	Hs
		988504 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		NOSTN_HUMAN (17-231): 1.08e-10: 66.8: 15.70
+	Hs
		955353 CDC42_HUMAN (1-191): 1.47e-79: 236: 80.11		NOSTN_HUMAN (17-231): 1.08e-10: 66.8: 15.70