HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: NOSTN (Q8IVI9)
Nostrin (BM247 homolog) (Nitric oxide synthase traffic inducer) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer)
Gene: NOSTRIN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22751148
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 506
+	Hs
		988825 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		PACN2_HUMAN (6-496): 6.47e-61: 209: 15.81
+	Hs
		988316 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		FCHO2_HUMAN (11-432): 7.77e-49: 181: 14.59
+	Hs
		581011 RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19		FCHO2_HUMAN (11-432): 7.77e-49: 181: 14.59
+	Hs
		1070514 RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64		FCHO2_HUMAN (11-432): 7.77e-49: 181: 14.59
+	Hs
		988631 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		FNBP1_HUMAN (14-380): 4.13e-46: 171: 16.31
+	Hs
		988326 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		MYO1E_HUMAN (18-495): 3.66e-41: 160: 13.55
+	Hs
		988485 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		SRGP1_HUMAN (15-468): 4.82e-41: 160: 11.13
+	Hs
		581015 RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19		MYO1E_HUMAN (18-495): 3.66e-41: 160: 13.55
+	Hs
		1091716 RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64		MYO1E_HUMAN (18-495): 3.66e-41: 160: 13.55
+	Gg
		1221097 Q6LC82_CHICK (1-192): 4.32e-85: 250: 100.00		ARHG6_CHICK (417-506): 1.92e-28: 121: 35.79
+	Hs
		988376 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		ARHG6_HUMAN (427-506): 4.33e-26: 114: 37.50
+	Hs
		581059 RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19		ARHG6_HUMAN (427-506): 4.33e-26: 114: 37.50
+	Hs
		1140198 RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64		ARHG6_HUMAN (427-506): 4.33e-26: 114: 37.50
+	Hs
		988358 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		ARHG7_HUMAN (432-506): 4.27e-22: 102: 33.33
+	Hs
		581039 RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19		ARHG7_HUMAN (432-506): 4.27e-22: 102: 33.33
+	Hs
		1121983 RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64		ARHG7_HUMAN (432-506): 4.27e-22: 102: 33.33
+	Hs
		988810 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		PACN3_HUMAN (110-495): 1.83e-11: 68: 12.22
+	Hs
		988427 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		FBP1L_HUMAN (291-492): 2.22e-10: 64.9: 16.18
+	Hs
		269537 RAC1_HUMAN (1-192): 4.32e-85: 250: 100.00		SRGP2_HUMAN (31-506): 1.08e-09: 63.3: 12.18
+	Hs
		1211652 RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64		FBP1L_HUMAN (291-492): 2.22e-10: 64.9: 16.18